Journal: Neurochemistry international

Article Title: Cannabinoid-profiled agents improve cell survival via reduction of oxidative stress and inflammation, and Nrf2 activation in a toxic model combining hyperglycemia+Aβ 1-42 peptide in rat hippocampal neurons.

doi: 10.1016/j.neuint.2020.104817

Figure Lengend Snippet: Fig. 13. Effects of increased concentrations (1–1000 nM, for 6 h) of anandamide (AEA), 2-arachidonoylglycerol (2-AG), CP 55–940, WIN 55,212–2, and URB597, on inducible-nitric oxide synthase (iNOS; A), Interleukin-1β (IL-1β; B), and Tumor Necrosis Factor-α (TNF-α; C) levels in primary hippocampal neurons exposed to high glucose (GLU; 150 mM for 48 h) + amyloid β peptide (Aβ1-42; 500 nM for 24 h). Data are mean values ± S.E.M. of n = 2 experiments per assay. **P ≤0.01 and ʄP ≤ 0.001, different from the control group; +P ≤0.05, ++P ≤0.01 and ɸP ≤0.001, different from the GLU + Aβ1-42 group; Kruskal-Wallis ANOVA with uncorrected Dunn’s test.

Article Snippet: Rat Inducible Nitric Oxide Synthase (iNOS) ELISA kit and Rat 3-nitrotyrosine (3-NT) ELISA kit were obtained from Cusabio Technology LLC (Houston, TX, USA).

Techniques: Control

Journal: Evidence-based Complementary and Alternative Medicine : eCAM

Article Title: Naoxintong Protects Primary Neurons from Oxygen-Glucose Deprivation/Reoxygenation Induced Injury through PI3K-Akt Signaling Pathway

doi: 10.1155/2016/5815946

Figure Lengend Snippet: Effects of BNC on mPTP opening, cytochrome-c release, and ΔΨ m in neurons following OGD induced injury. (a) mPTP opening was detected by calcein fluorescence. (b) Cytochrome-c release was measured by ELISA. (c) ΔΨ m was indicated by the ratio of fluorescence red (J-aggregates) to green (JC-1). Data are expressed as mean + SD. n = 6 per group. ## P < 0.01 compared with control; ∗ P < 0.05, ∗∗ P < 0.01 compared with OGD/R.

Article Snippet: Cytochrome-C ELISA kit and neuronal Nitric Oxide Synthase ELISA kit were obtained from Cusabio (Wuhan, China).

Techniques: Fluorescence, Enzyme-linked Immunosorbent Assay, Control